💩 From Bloated to Balanced: How These Enzymes Saved Me Mid-Tirzepatide Constipation

 I don’t usually write about what happens after dinner… but let’s just say yesterday deserved a post.

I’m on week 147 of tirzepatide (shoutout to my Friday night injection crew), and despite having my routine mostly dialed in, I got hit hard with brick wall constipation this week.

No warning. Just... 💥 stuck.

So I did what I regularly do: I reached for my Physician’s Choice Digestive Enzymes.

I bought them a while back for “just in case” moments. Yesterday? It was the case.

And y’all — they worked.

But this post isn’t just about relief. It’s about understanding what you’re actually putting in your body — especially when you're navigating the layered effects of GLP-1s like tirzepatide.

Let’s unpack the ingredient blend and why it matters:


🧪 What’s Inside These Capsules — And Why It Works

These enzymes go way beyond the basics. Here’s what you’re really getting in every serving:

1. Protease Blend (5 Types)

  • Breaks down proteins into amino acids

  • Key for bloating from protein-heavy meals or shakes

  • Helps when your digestion slows down due to GLP-1 meds

2. Amylase

  • Breaks down carbs into sugars

  • Crucial for balanced energy and minimizing sugar spikes post-meal

3. Lipase

  • Digests fats

  • Game-changer for fatty meals and post-meal fatigue

4. Bromelain + Papain

  • Natural anti-inflammatories (from pineapple + papaya)

  • Soothes the gut and reduces digestive stress

5. Cellulase

  • Breaks down plant fibers (like veggies and legumes)

  • A must-have if fiber constipates you more than it helps

6. Lactase

  • Helps digest lactose

  • If dairy bloats you, this will soften the blow

7. Invertase

  • Converts sugar into more digestible forms

  • Supports smoother sugar digestion and less “sugar slump”

8. Prebiotic Fiber (Organic Blend)

  • Supports your good gut bacteria

  • Think of it as fertilizer for your microbiome

9. Probiotics (Bacillus subtilis)

  • Spore-based, shelf-stable strain

  • Helps repopulate and balance the gut, especially post-antibiotics or medication-related disruption


🌿 Why This Hits Different on GLP-1s

If you’re on tirzepatide or any GLP-1 med, your digestion slows down — it’s part of how it helps with satiety and blood sugar. But that also means...

➡️ You’re more prone to constipation
➡️ Food hangs around in your gut longer
➡️ Even small meals can feel heavy

Digestive enzymes step in where your own system might be lagging. They help your body actually break down what you eat — before it becomes a traffic jam in your colon.


Final Word

This isn’t a daily must-have for me. But when my gut says, “We’re stuck,” this is my go-to fix.

If you’re on a GLP-1 journey and navigating surprise bloat or backup, don’t sleep on enzyme support. It’s not a miracle — but it’s a mighty helper.

🧃 A Final Win for My Gut — and My Wallet

Here’s what really makes this a win for me:
I’ve been recommending digestive enzymes for years — to friends, followers, even my own family. But it’s always come with a disclaimer: they’re helpful, but pricey… and not all blends are created equal.

That’s why I’m genuinely relieved (and kinda excited?) to say:
I’ve finally found one that works — and doesn’t wreck my budget.

Physician’s Choice Digestive Enzymes are not only effective — especially when tirzepatide hits hard — but also accessible.
This is the kind of support I wish I had from day one. Now I do.

And if you’re in the same boat?
This might be your “relief without regret” moment too.


💬 What about you?

Ever had to pull out the “emergency enzyme” card? Or found a blend that actually works for your GLP-1 gut? Drop your favorite support tools in the comments — we’re in this together.

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